1/7/2024 0 Comments Zombie quest![]() This scientific renown didn't come easily. Before him on the living room table are numerous copies of his seminal book, "How and Why We Age," in various languages. He's a professor of anatomy at the University of California, San Francisco, and continues to write, present and speak on the topic.Īt his seaside home in Sonoma County, he leafs through a binder filled with his research, including two early papers that have been cited an astonishing number of times by other researchers. Leonard Hayflick, the scientist who discovered cellular senescence in 1960, is himself vital at 94. ![]() According to an Associated Press analysis of an NIH research database, there have been around 11,500 total projects involving cellular senescence since 1985, far more in recent years.Īn over 60 years and older group of women run a 200 meter race during the National Senior Games, Monday, May 16, 2022, in Miramar,Fla. With the number of people 65 or older expected to double globally by 2050, cellular senescence is "a very hot topic," says Viviana Perez Montes of the National Institutes of Health. Extending the span of healthy years impacts "quality of life, public health, socioeconomics, the whole shebang." "The ability to understand aging-and the potential to intervene in the fundamental biology of aging-is truly the greatest opportunity we have had, maybe in history, to transform human health," LeBrasseur says. But he and his wife Jean quit cold turkey when their daughter Mary came along. After a torn hamstring stopped him from running track in high school, he fell into an unhealthy lifestyle in early adulthood, smoking two packs of cigarettes a day. Richard Soller, 95, runs in the 200 meter race for men over 85 years old at the National Senior Games, Monday, May 16, 2022, in Miramar, Fla. They accumulate in older bodies, which mounting evidence links to an array of age-related conditions such as dementia, cardiovascular disease and osteoporosis.īut scientists wonder: Can the zombie cell buildup be stopped? But as the Mayo Clinic's Nathan LeBrasseur puts it, they can harm nearby cells like moldy fruit corrupting a fruit bowl. It's built upon the idea that cells eventually stop dividing and enter a "senescent" state in response to various forms of damage. But scientists are trying to change that-and tackle one of humanity's biggest challenges-through a little known but flourishing field of aging research called cellular senescence. It's a goal that eludes so many that growing old is often associated with getting frail and sick. Soller, who lives near Cincinnati, has achieved an enviable goal chased by humans since ancient times: Staying healthy and active in late life. He proudly proclaims he's never used it he's been too busy training for competitions, such as the National Senior Games. ![]() Steps away is an expensive leather recliner he bought when he retired from Procter & Gamble with visions of relaxing into old age. Without a hint of breathlessness, he says: "I can put in miles down here."
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